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Project Medical Education Returns to CUIMC

Source:

CUIMC newsroom

September 8, 2022

This past August, after a two-year hiatus, Project Medical Education (PME) returned to Columbia University Irving Medical Center (CUIMC).
Comparative functional genomics identifies unique molecular features of EPSCs

Source:

Life Science Alliance

September 8, 2022

We provide a rich resource for dissecting the regulatory network that governs the developmental potency of EPSCs and exploring alternative strategies to capture totipotent stem cells in culture.
Stavroula Kousteni, PhD, has been awarded a 2022 EvansMDS Cancer Discovery Research Grant

Source:

EvansMDS

August 22, 2022

The Cancer Discovery Research award provides recipients with funding at $200,000 per year for up to three years.
Aaron Viny Wins Doris Duke Clinical Scientist Development Award

Source:

Columbia HICCC News

August 22, 2022

Aaron Viny, MD, assistant professor of medicine at VP&S, joins 16 recipients recognized for research that has the potential to advance the prevention, diagnosis and treatment of human disease.
Spatial profiling of chromatin accessibility in mouse and human tissues

Source:

Nature

August 17, 2022

Here we describe a method for spatially resolved chromatin accessibility profiling of tissue sections using next-generation sequencing.
Efficient Cas9-based Genome Editing Using CRISPR Analysis Webtools in Severe Early-onset-obesity Patient-derived iPSCs

Source:

Current Protocols

August 11, 2022

Discovery of the CRISPR-associated protein Cas9 and its RNA-guided cleavage mechanism marks the beginning of a new era in genomic engineering by enabling the editing of a target region in the genome.
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Source:

Nature communications

August 1, 2022

Our results uncover a unifying stress-response pathway causally linking Aβ42o-dependent structural remodeling of dendritic mitochondria to synaptic loss.
Potential ALS Treatment Emerges from Nerve Cells in a Dish

Source:

CUIMC newsroom

July 25, 2022

Today Hynek Wichterle, PhD, and his colleagues are tantalizingly close to bringing a new drug for amyotrophic lateral sclerosis (ALS) to market.
Replication stress impairs chromosome segregation and preimplantation development in human embryos

Source:

Cell

July 19, 2022

The findings provide new insights into the basic biology of human reproduction and in the long term could lead to improvements in the success rate of in vitro fertilization (IVF).
Study Finds Why Many IVF Embryos Fail to Develop

Source:

CUIMC newsroom

July 19, 2022

Researchers have found that most of these mistakes are due to spontaneous errors in DNA replication in the earliest phase of cell division.

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