Columbia Stem Cell Initiative

Tapping the Potential of Stem Cells for Human Health

At the Columbia Stem Cell Initiative (CSCI) we are building a cutting-edge, premier stem cell program that integrates expertise in regeneration and precision medicine and shapes a novel basic and translational understanding of stem cells in health and disease for biomedical research.

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Who We Are

Providing investigators with access to advanced equipment and resources for stem cell research.

Meet Our Members

Core Facilities

Providing investigators with access to advanced equipment and resources for stem cell research.

Go to Our Core Facilities

Jobs

Providing investigators with access to advanced equipment and resources for stem cell research.

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Announcements

Emmanuelle Passegué, PhD, is a featured panelist for the December 8 Leadership Pathways for Women Faculty: Strategies for Navigating Uncertain Times

This program includes a panel discussion of senior women faculty leaders and facilitated peer mentoring sessions that focuses on the challenges of academic leadership and advancement for women.
CSCI strongly supports the use of human embryonic stem cells in research

Human embryonic stem cells are essential for our understanding of human development and disease.
UPDATED; Announcing the Spring Stem Cells, Genome Engineering and Regenerative Medicine Course

The lectures will include general lectures on stem cell biology followed by student presentations and discussion of the primary literature.
Kelley Yan one of 85 new NIH grants featuring high-risk, high-reward research

The 2020 Director’s Awards will feature highly innovative biomedical research by investigators at all career stages.
Christoph Anacker and Pietro Mazzara are 2 of the recipients of the Brain & Behavior Research Foundation Awards

Christoph Anacker, Ph.D. and Pietro Mazzara, Ph.D (from the Kristin Baldwin lab) are recipients of The Brain & Behavior Research Foundation Young Investigator Grants.

Meet the Director of the Columbia Stem Cell Initiative

Dr. Passegue of the Columbia Stem Cell Initiative

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Events

Columbia Stem Cell Initiative (CSCI)Work in Progress (WIP) Series

Thursday, December 3, 2020

11:30 AM to 12:30 PM

Venue

Online
CSCI Seminar Series with Ken Poss

Thursday, December 10, 2020

11:30 AM to 12:30 PM

Venue

Online
CSCI Seminar Series with Madeline Lancaster

Thursday, January 21, 2021

11:30 AM to 12:30 PM

Venue

Online

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News

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

Source:

eLife

September 30, 2020

Here, we describe a comprehensive single-cell atlas of the adult mouse prostate epithelium, which displays extensive heterogeneity.
Lineage analysis reveals an endodermal contribution to the vertebrate pituitary

Source:

Science

October 23, 2020

In addition to known ectodermal contributions, we use lineage tracing and time-lapse imaging in zebrafish to identify an endodermal contribution to the ADH.
Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

Source:

Cell

October 30, 2020

Here, we evaluate repair outcomes of a Cas9-induced double-strand break (DSB) introduced on the paternal chromosome at the EYS locus, which carries a frameshift mutation causing blindness.