Forebrain organoids generated from human induced pluripotent stem cells derived from subjects with well-characterized brain disorders are a promising method to study human-specific neurobiology.
We define the integrin adhesome expression profile of NK cells from human tonsil, peripheral blood, and those derived from human hematopoietic precursors through stromal cell coculture systems.
The transcriptional regulators underlying induction and differentiation of dense connective tissues such as tendon and related fibrocartilaginous tissues remain largely unknown.
Vunjak-Novakovic's ground-breaking approach offers a safer, more precise and less intrusive facial reconstruction method and holds promise for replacing damaged lung and heart tissue.
Using a Sendai virus-based approach, the four reprogramming factors OCT3/4, SOX2, KLF4 and C-MYC were delivered into Peripheral Blood Mononuclear Cell from a 14-year-old girl with early onset obesity.
This review focuses on inflammatory signaling in the emergence of the definitive hematopoietic compartment during embryonic life, and tonic inflammatory signals derived from commensal microbiota...
Here we describe a protocol for in-parallel generation of cortical glutamatergic (excitatory) and GABAergic (inhibitory) neurons from human pluripotent stem cells (hPSCs.)