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Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia

Source:

Journal of Experimental Medicine

Targeting commonly altered mechanisms in leukemia can provide additional treatment options.
In vitro models of neuromuscular junctions and their potential for novel drug discovery and development

Source:

Expert Opinion on Drug Discovery

Neuromuscular Junctions (NMJs) are the synapses between motor neurons and skeletal muscle fibers, and they are responsible for voluntary motor function.
Compound heterozygous novel frameshift variants in the PROM1 gene result in Leber congenital amaurosis.

Source:

Cold Spring Harbor Laboratory Press

Compound heterozygous novel frameshift variants in the PROM1 gene result in Leber congenital amaurosis.
Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations

Source:

Scientific Reports

Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations

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These secret battles between your body’s cells might just save your life

Source:

Nature

October 15, 2019

To fight cancer and ageing, biologists are looking at how cells evict, kill or cannibalize less-fit rivals.
New Tools in the Works to Probe Adult Human Neurogenesis

Source:

The Scientist

October 7, 2019

Conflicting results on the existence of new neurons in adults have researchers designing new ways to identify and count neuronal progenitors—and finally get to the bottom of neurogenesis.
Columbia Scientists Demonstrate Power of High-Speed Microscope to Illuminate Biology at the Speed of Life

Source:

Zuckerman Institute

September 27, 2019

New SCAPE 2.0 system can serve as a critical tool to advance science and medicine
Engineering human tissues to transform biomedical engineering

Source:

NIH

September 20, 2019

Trailblazer Gordana Vunjak-Novakovic, Ph.D., expertly manipulates a cell’s environment to change its behavior and function.
Anxiety, 'Fight or Flight' Response: Humans Really Do Feel Fear in Their Bones, Study Finds

Source:

Newsweek

September 14, 2019

Gerard Karsenty is one of the scientists behind a decades-long exploration of the human fight-or-flight response.
Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype

Source:

Nature Protocols

September 6, 2019

Advances in stem cell biology and tissue engineering have led to the development of engineered tissue models or ‘organs-on-a-chip.’