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Developmental BiologyHere we report two distinct roles of Gon4l/Udu in heart development: regulation of cell proliferation and maintenance of ventricular identity.
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NatureOptogenetic genome engineering tools enable spatiotemporal control of gene expression and provide new insight into biological function.
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NatureHere we describe how selection for specific mutations that increase HSC competitive fitness, in conjunction with additional endogenous and environmental changes, drives leukaemic transformation.
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Investigative Ophthalmology & Visual ScienceWe tested whether sodium phenylbutyrate (4PBA) could rescue the function of mutant bestrophin 1 associated with autosomal dominant and recessive disease.
