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Source:Cell Stem Cell
Advances in tissue mimetics are paving the way for interrogating both the pathobiology of human disease and innovative therapeutic paradigms
Source:American Journal of Human Genetics
Macular degeneration (MD) is characterized by the progressive deterioration of the macula and represents one of the most prevalent causes of blindness worldwide.
Entering through angiotensin-converting enzyme 2 receptors,2 SARS-CoV-2 can damage endothelial cells leading to inflammation, thrombi, and brain damage.
We sought to identify a method of testing that would provide patient-specific information on whether a patient will respond to a medication using in vitro modeling.
Source:Cell Stem CellApril 1, 2021
Through social media and our reviewer networks, we met some early-career stem cell investigators impacted by the closures.
Source:PNASFebruary 8, 2021
We demonstrate that iBMECs lack functional attributes of ECs since they are deficient in vascular lineage genes while expressing clusters of genes related to the neuroectodermal epithelial lineage.
Source:Cell Stem CellFebruary 5, 2021
COVID-19 has unfortunately halted lab work, conferences, and in-person networking, which is especially detrimental to researchers just starting their labs.
Source:DevelopmentJanuary 27, 2021
We report adult viable nkx3.2 mutant zebrafish displaying cartilage overgrowth in place of a missing jaw joint, as well as severe dysmorphologies of the facial skeleton, skullcap and spine.
Source:Stem Cell ReportsNovember 10, 2020
Androgen receptor (AR) plays a fundamental role in most aspects of adult prostate homeostasis, and anti-androgen therapy represents the cornerstone of prostate cancer treatment.
Source:Journal of Experimental MedicineNovember 5, 2020
Here, we genetically dissected the developing liver niche by systematically determining the cellular source of a key HSC niche factor, stem cell factor (SCF).