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Source:European Patent Office
Vunjak-Novakovic's ground-breaking approach offers a safer, more precise and less intrusive facial reconstruction method and holds promise for replacing damaged lung and heart tissue.
How engineers are working with biologists and oncologists to model the progression of cancer and uncover new treatments.
Source:Journal of Experimental Medicine
We used transplantation, parabiosis, plasma transfer, exercise, calorie restriction, and aging mutant mice to understand the effects of age-regulated systemic factors on HSCs and bone marrow niche.
Source:Cell Stem Cell
We discuss the potential of “organ-on-a-chip” systems to study regenerative therapies with focus on three distinct organ systems: cardiac, respiratory, and hematopoietic.
Source:Stem Cell ResearchJune 21, 2021
Using a Sendai virus-based approach, the four reprogramming factors OCT3/4, SOX2, KLF4 and C-MYC were delivered into Peripheral Blood Mononuclear Cell from a 14-year-old girl with early onset obesity.
Source:Journal of Experimental MedicineJune 15, 2021
This review focuses on inflammatory signaling in the emergence of the definitive hematopoietic compartment during embryonic life, and tonic inflammatory signals derived from commensal microbiota...
Source:Current ProtocolsJune 8, 2021
Here we describe a protocol for in-parallel generation of cortical glutamatergic (excitatory) and GABAergic (inhibitory) neurons from human pluripotent stem cells (hPSCs.)
Source:Genetics Society of AmericaMay 28, 2021
In the Decoding Life series, we talk to geneticists with diverse career paths, tracing the many directions possible after research training.
Source:American Journal of Human GeneticsMay 6, 2021
Macular degeneration (MD) is characterized by the progressive deterioration of the macula and represents one of the most prevalent causes of blindness worldwide.
Source:Cell Stem CellMay 6, 2021
Advances in tissue mimetics are paving the way for interrogating both the pathobiology of human disease and innovative therapeutic paradigms