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Autism spectrum disorder (ASD) represents a major public health burden but translating promising treatment findings from preclinical non-human models of ASD to the clinic has remained challenging.
The bone marrow niche plays a critical role in hematopoietic recovery and hematopoietic stem cell (HSC) regeneration after myeloablative stress.
This project will study the signaling and biomechanics of embryo implantation and failure
Source:European Patent Office
Vunjak-Novakovic's ground-breaking approach offers a safer, more precise and less intrusive facial reconstruction method and holds promise for replacing damaged lung and heart tissue.
Source:Nature communicationsSeptember 1, 2021
Forebrain organoids generated from human induced pluripotent stem cells derived from subjects with well-characterized brain disorders are a promising method to study human-specific neurobiology.
Source:The Journal of ImmunologyAugust 16, 2021
We define the integrin adhesome expression profile of NK cells from human tonsil, peripheral blood, and those derived from human hematopoietic precursors through stromal cell coculture systems.
Source:Nature communicationsJuly 9, 2021
The transcriptional regulators underlying induction and differentiation of dense connective tissues such as tendon and related fibrocartilaginous tissues remain largely unknown.
Source:Columbia NewsJune 24, 2021
How engineers are working with biologists and oncologists to model the progression of cancer and uncover new treatments.
Source:Stem Cell ResearchJune 21, 2021
Using a Sendai virus-based approach, the four reprogramming factors OCT3/4, SOX2, KLF4 and C-MYC were delivered into Peripheral Blood Mononuclear Cell from a 14-year-old girl with early onset obesity.
Source:Journal of Experimental MedicineJune 15, 2021
This review focuses on inflammatory signaling in the emergence of the definitive hematopoietic compartment during embryonic life, and tonic inflammatory signals derived from commensal microbiota...