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Source:Cell Stem Cell
COVID-19 has unfortunately halted lab work, conferences, and in-person networking, which is especially detrimental to researchers just starting their labs.
We demonstrate that iBMECs lack functional attributes of ECs since they are deficient in vascular lineage genes while expressing clusters of genes related to the neuroectodermal epithelial lineage.
We report adult viable nkx3.2 mutant zebrafish displaying cartilage overgrowth in place of a missing jaw joint, as well as severe dysmorphologies of the facial skeleton, skullcap and spine.
Source:Stem Cell Reports
Androgen receptor (AR) plays a fundamental role in most aspects of adult prostate homeostasis, and anti-androgen therapy represents the cornerstone of prostate cancer treatment.
Source:Journal of Experimental MedicineNovember 5, 2020
Here, we genetically dissected the developing liver niche by systematically determining the cellular source of a key HSC niche factor, stem cell factor (SCF).
Source:The New York TimesOctober 31, 2020
Instead of addressing genetic mutations, the Crispr machinery prompted cells to lose entire chromosomes.
Source:Rita Allen FoundationOctober 30, 2020
Emmanuelle Passegué featured in the Rita Allen Foundation Scholar Profiles
Source:CellOctober 30, 2020
Here, we evaluate repair outcomes of a Cas9-induced double-strand break (DSB) introduced on the paternal chromosome at the EYS locus, which carries a frameshift mutation causing blindness.
Source:ScienceOctober 23, 2020
In addition to known ectodermal contributions, we use lineage tracing and time-lapse imaging in zebrafish to identify an endodermal contribution to the ADH.
Source:StemBookOctober 23, 2020
The Stem Cell Core Facility is one of the two core facilities of the Columbia Stem Cell Initiative (CSCI), the major stem cell program at the Columbia University Irving Medical Center.