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Source:Columbia Engineering News
A team of researchers from reports that they have essentially created a plug-and-play multi-organ chip, which is the size of a microscope slide, that can be customized to the patient.
Kelley Yan and Aaron Viny among 15 who have been recognized as VP&S Promising Clinician Scientists and awarded grants from the Office of Academic Affairs to support their research.
Source:The Journal of Clinical Investigation
Here, we detail recent advancements in CRISPR therapeutics to treat a wide range of autosomal dominant disorders and discuss how they are altering the landscape for future therapies.
Remodeling of the microenvironment by tumor cells can activate pathways that favor cancer growth.
Source:Nature Biomedical EngineeringMay 2, 2022
Vascularly linked and phenotypically stable matured human tissues may facilitate the clinical applicability of tissue chips.
Source:Human Molecular GeneticsApril 25, 2022
This study demonstrates the remarkable robustness of the human replication timing program and reveals MCM10 as a novel candidate modulator of DNA replication timing.
Source:Cell PressApril 18, 2022
Totipotent stem cells are transiently occurring in vivo cells that can form all cell types of the embryo including placenta, with their in vitro counterparts being actively pursued.
Source:Methods in Molecular BiologyMarch 29, 2022
Here, we will describe techniques for the experimental setup and analysis of NK cell motility assays by confocal microscopy or in-incubator imaging using commercially available systems.
Source:Columbia HICCC NewsMarch 21, 2022
Timothy Wang, MD, and Kelley Yan, MD, PhD, have each been awarded 2022 Annual Recognition Prizes from the American Gastroenterological Association (AGA).
Source:Stem Cells and DevelopmentMarch 14, 2022
We highlight human induced pluripotent stem cells (hiPSCs) as the advantageous cell source for these models and review approaches for chondrogenic fate specification from hiPSCs.