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Showing 101 - 110 of 256 results.

Pparg signaling controls bladder cancer subtype and immune exclusion

Source:

Nature communications

October 25, 2021

Our findings have important implications for treatment and diagnosis of bladder cancer.
Investigating Adult Stem Cells Through Lineage analyses

Source:

Stem Cell Reviews and Reports

October 22, 2021

Discussion of appropriate general definition of adult stem cells and use of lineage methods to determine numbers, location and behavior of stem cells.
Rene Hen One of Three VP&S Faculty Members Elected to the National Academy of Medicine

Source:

CUIMC newsroom

October 19, 2021

The National Academy of Medicine announced new members elected to the academy, including René Hen, PhD, professor of neuroscience and molecular pharmacology & therapeutics (in psychiatry).
Mijo Simunovic One of Six Columbia Scientists Awarded NIH High-Risk, High-Reward Grants

October 5, 2021

NIH High-Risk, High-Reward grants given to exceptionally creative scientists proposing unconventional, but potentially high-impact, research that addresses major challenges in medicine.
Adult stem cells and niche cells segregate gradually from common precursors that build the adult Drosophila ovary during pupal development

Source:

eLife

October 1, 2021

ECs, FSCs, and FCs develop from common pupal precursors, with different fates acquired by progressive separation of cells along the AP axis and a graded decline in anterior cell proliferation.
Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Source:

Current Protocols

September 13, 2021

We leverage recent advances in transcriptomics and proteomics research to identify cell-type-specific metabolic features.
Thrombopoietin from hepatocytes promotes hematopoietic stem cell regeneration after myeloablation

Source:

eLife

September 13, 2021

The bone marrow niche plays a critical role in hematopoietic recovery and hematopoietic stem cell (HSC) regeneration after myeloablative stress.
Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder

Source:

Nature communications

September 1, 2021

Forebrain organoids generated from human induced pluripotent stem cells derived from subjects with well-characterized brain disorders are a promising method to study human-specific neurobiology.
Differential Integrin Adhesome Expression Defines Human NK Cell Residency and Developmental Stage

Source:

The Journal of Immunology

August 16, 2021

We define the integrin adhesome expression profile of NK cells from human tonsil, peripheral blood, and those derived from human hematopoietic precursors through stromal cell coculture systems.
Mijo Simunovic Earns Grant to Investigate Early Pregnancy

Source:

Columbia Engineering

August 6, 2021

This project will study the signaling and biomechanics of embryo implantation and failure

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