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Showing 101 - 110 of 200 results.
Despite its ubiquitous expression on human NK cells the role of CD56 (NCAM) in human NK cell cytotoxic function has not been defined.
We tested whether sodium phenylbutyrate (4PBA) could rescue the function of mutant bestrophin 1 associated with autosomal dominant and recessive disease.
Here we describe how selection for specific mutations that increase HSC competitive fitness, in conjunction with additional endogenous and environmental changes, drives leukaemic transformation.
In this short review, we draw parallels and stress differences between heart regeneration in mice and human, from a bioengineering perspective.
Optogenetic genome engineering tools enable spatiotemporal control of gene expression and provide new insight into biological function.
Here we consider how changing migratory and adhesive phenotypes contribute to human natural killer (NK)- and T-cell development
We review recent advances in lung bioengineering that have potential to repair the epithelial and vascular compartments of the lung
Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine
Maintenance of a healthy photoreceptor-retinal pigment epithelium (RPE) interface is essential for vision.
Major breakthroughs in stem cell differentiation to therapeutically relevant cell types have led us to the doorstep of novel cell therapies that can replace disease management with a cure.