A biomarker has been identified by a multicenter research team that predicts which stage II colon cancer patients may benefit from chemotherapy after surgery to prevent a recurrence of their disease.
This paper characterizes the block to infection of mouse induced pluripotent stem cells (iPSC) by HIV vectors. The findings are relevant to gene therapy approaches targeting these cells.
This paper probes the mechanisms by which embryonic stem cells regulate the levels of ZFP809, the major repressor of murine leukemia virus gene expression.
A new CRISPR-dependent approach to inactivate genes by inducing STOP codons by generating knockout alleles in stem cells without formation of potentially toxic DNA double-strand breaks.
