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Totipotent stem cells are transiently occurring in vivo cells that can form all cell types of the embryo including placenta, with their in vitro counterparts being actively pursued.
Kelley Yan and Aaron Viny among 15 who have been recognized as VP&S Promising Clinician Scientists and awarded grants from the Office of Academic Affairs to support their research.
Remodeling of the microenvironment by tumor cells can activate pathways that favor cancer growth.
Here, we will describe techniques for the experimental setup and analysis of NK cell motility assays by confocal microscopy or in-incubator imaging using commercially available systems.
Timothy Wang, MD, and Kelley Yan, MD, PhD, have each been awarded 2022 Annual Recognition Prizes from the American Gastroenterological Association (AGA).
We highlight human induced pluripotent stem cells (hiPSCs) as the advantageous cell source for these models and review approaches for chondrogenic fate specification from hiPSCs.
Chao Lu, PhD has been awarded the prestigious 2022 Hirschl Trust Research Awards by the Irma T. Hirschl Trust Research Scientist Program.
We aimed to identify miRNAs that are upregulated during terminal differentiation in the human colon epithelium, and elucidate their role in the mechanistic control of stem cell properties.
This study demonstrates the effectiveness of AR treatment of adRP in the human genomic context while revealing the feasibility of its application for other autosomal dominant disorders.
Our study demonstrates that SIGMAR1 is a potential therapeutic target for Timothy syndrome and possibly other inherited arrhythmias such as LQTS1 and LQTS2.