Taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents.
A deficiency of taurine is a driver of aging in animals, according to a new study led by Columbia researchers and involving dozens of aging researchers around the world.
We performed lineage tracing and found that most collagen-expressing myofibroblasts were derived from leptin-receptor-positive mesenchymal cells, whereas a minority were from Gli1-lineage cells.
Chia-Wei Cheng, PhD, has recently been awarded a V Foundation grant for her innovative research in the interface of nutritional and gene regulatory networks in cancer.
Drs. Lu & Simunovic among five VP&S faculty to receive a Schaefer Scholar Award this year, recognizing scientists who have distinguished themselves in the science of human physiology.
This study highlights the novel myelopoiesis-regulatory population that amplifies myeloid cell production through lineage priming and cytokine secretion in inflammatory and disease conditions.
A previously uncharacterized CERT1 domain enables its homeostatic inactivation, without which sphingolipid production goes unchecked; clinical severity reflects the degree of dysregulation
RNA-binding proteins such as PUM1 regulate mRNA targets in various ways. But to understand their physiological functions we have to study their interactions as well as targets.