Here, we detail recent advancements in CRISPR therapeutics to treat a wide range of autosomal dominant disorders and discuss how they are altering the landscape for future therapies.
A team of researchers from reports that they have essentially created a plug-and-play multi-organ chip, which is the size of a microscope slide, that can be customized to the patient.
This study demonstrates the remarkable robustness of the human replication timing program and reveals MCM10 as a novel candidate modulator of DNA replication timing.
Totipotent stem cells are transiently occurring in vivo cells that can form all cell types of the embryo including placenta, with their in vitro counterparts being actively pursued.
Kelley Yan and Aaron Viny among 15 who have been recognized as VP&S Promising Clinician Scientists and awarded grants from the Office of Academic Affairs to support their research.
Here, we will describe techniques for the experimental setup and analysis of NK cell motility assays by confocal microscopy or in-incubator imaging using commercially available systems.
Timothy Wang, MD, and Kelley Yan, MD, PhD, have each been awarded 2022 Annual Recognition Prizes from the American Gastroenterological Association (AGA).
We highlight human induced pluripotent stem cells (hiPSCs) as the advantageous cell source for these models and review approaches for chondrogenic fate specification from hiPSCs.
