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Showing 1 - 10 of 99 results.
Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations
Neuromuscular Junctions (NMJs) are the synapses between motor neurons and skeletal muscle fibers, and they are responsible for voluntary motor function.
We tested whether sodium phenylbutyrate (4PBA) could rescue the function of mutant bestrophin 1 associated with autosomal dominant and recessive disease.
Here we describe how selection for specific mutations that increase HSC competitive fitness, in conjunction with additional endogenous and environmental changes, drives leukaemic transformation.
In this short review, we draw parallels and stress differences between heart regeneration in mice and human, from a bioengineering perspective.
Optogenetic genome engineering tools enable spatiotemporal control of gene expression and provide new insight into biological function.
Here we consider how changing migratory and adhesive phenotypes contribute to human natural killer (NK)- and T-cell development
We review recent advances in lung bioengineering that have potential to repair the epithelial and vascular compartments of the lung
Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine
Maintenance of a healthy photoreceptor-retinal pigment epithelium (RPE) interface is essential for vision.