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Showing 131 - 140 of 261 results.

Chia-Wei Cheng featured in Cell Stem Cell's "Introductions to the community: Early-career researchers in the time of COVID-19"

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Cell Stem Cell

April 1, 2021

Through social media and our reviewer networks, we met some early-career stem cell investigators impacted by the closures.
How COVID-19 affects the brain

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JAMA Psychiatry

March 26, 2021

Entering through angiotensin-converting enzyme 2 receptors,2 SARS-CoV-2 can damage endothelial cells leading to inflammation, thrombi, and brain damage.
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

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PNAS

February 8, 2021

We demonstrate that iBMECs lack functional attributes of ECs since they are deficient in vascular lineage genes while expressing clusters of genes related to the neuroectodermal epithelial lineage.
Aaron Viny featured in Cell Stem Cell's "Introductions to the Community: Early-Career Researchers in the Time of COVID-19"

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Cell Stem Cell

February 5, 2021

COVID-19 has unfortunately halted lab work, conferences, and in-person networking, which is especially detrimental to researchers just starting their labs.
Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton

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Development

January 27, 2021

We report adult viable nkx3.2 mutant zebrafish displaying cartilage overgrowth in place of a missing jaw joint, as well as severe dysmorphologies of the facial skeleton, skullcap and spine.
Bipotent Progenitors Do Not Require Androgen Receptor for Luminal Specification during Prostate Organogenesis

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Stem Cell Reports

November 10, 2020

Androgen receptor (AR) plays a fundamental role in most aspects of adult prostate homeostasis, and anti-androgen therapy represents the cornerstone of prostate cancer treatment.
Hepatic stellate and endothelial cells maintain hematopoietic stem cells in the developing liver

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Journal of Experimental Medicine

November 5, 2020

Here, we genetically dissected the developing liver niche by systematically determining the cellular source of a key HSC niche factor, stem cell factor (SCF).
Crispr Gene Editing Can Cause Unwanted Changes in Human Embryos, Study Finds

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The New York Times

October 31, 2020

Instead of addressing genetic mutations, the Crispr machinery prompted cells to lose entire chromosomes.
Scholars Profile: Emmanuelle Passegué: Seeking the Secrets of Blood Stem Cells

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Rita Allen Foundation

October 30, 2020

Emmanuelle Passegué featured in the Rita Allen Foundation Scholar Profiles
Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

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Cell

October 30, 2020

Here, we evaluate repair outcomes of a Cas9-induced double-strand break (DSB) introduced on the paternal chromosome at the EYS locus, which carries a frameshift mutation causing blindness.

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