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Showing 141 - 150 of 242 results.

Gon4l/Udu regulates cardiomyocyte proliferation and maintenance of ventricular chamber identity during zebrafish development

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Developmental Biology

June 15, 2020

Here we report two distinct roles of Gon4l/Udu in heart development: regulation of cell proliferation and maintenance of ventricular identity.
Stargardt Juvenile Macular Degeneration

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The New England Journal of Medicine

June 11, 2020

A 13-year-old boy was referred to the ophthalmology clinic with enlarging blind spots in the central vision in both eyes.
CD56 regulates human NK cell cytotoxicity through Pyk2

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eLife

June 8, 2020

Despite its ubiquitous expression on human NK cells the role of CD56 (NCAM) in human NK cell cytotoxic function has not been defined.
Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium

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Investigative Ophthalmology & Visual Science

May 26, 2020

We tested whether sodium phenylbutyrate (4PBA) could rescue the function of mutant bestrophin 1 associated with autosomal dominant and recessive disease.
Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis

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Nature

May 15, 2020

Here we describe how selection for specific mutations that increase HSC competitive fitness, in conjunction with additional endogenous and environmental changes, drives leukaemic transformation.
Heart regeneration in mouse and human: a bioengineering perspective

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Science Direct

May 6, 2020

In this short review, we draw parallels and stress differences between heart regeneration in mice and human, from a bioengineering perspective.
Photoactivatable Cre recombinase 3.0 for in vivo mouse applications

Source:

Nature

May 1, 2020

Optogenetic genome engineering tools enable spatiotemporal control of gene expression and provide new insight into biological function.
From stem cell to immune effector: how adhesion, migration, and polarity shape T-cell and natural killer cell lymphocyte development in vitro and in vivo

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Molecular Biology of the Cell

April 30, 2020

Here we consider how changing migratory and adhesive phenotypes contribute to human natural killer (NK)- and T-cell development
Bioengineering of Pulmonary Epithelium With Preservation of the Vascular Niche

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Frontiers in Bioengineering and Biotechnology

April 15, 2020

We review recent advances in lung bioengineering that have potential to repair the epithelial and vascular compartments of the lung
Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine

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The Journal of Thoracic and Cardiovascular Surgery

April 3, 2020

Multiday maintenance of extracorporeal lungs using cross-circulation with conscious swine

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