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Precision Medicine, CRISPR, and Genome Engineering: Moving from Association to Biology and Therapeutics edited by Dr. Stephen Tsang

In this manuscript we point out the problem of the 'invisible allele' after gene editing in human embryos. Loss of a mutation is not equal to correction, and could instead be a new mutation.

Yazawa’s laboratory elucidates the molecular mechanism underlying cardiac phenotypes in Timothy syndrome patient-derived cardiomyocytes using induced pluripotent stem cell technology.