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Showing 151 - 160 of 256 results.

Severely Damaged Human Lungs Can Now Be Successfully Recovered

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Columbia Engineering

July 13, 2020

Columbia Engineering and Vanderbilt researchers demonstrate that human lungs rejected for transplant can be recovered
Does the Key to Anti-ageing Lie in Our Bones?

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The Guardian

July 4, 2020

Almost 15 years later, Gerard Karsenty would publish the first of a series of landmark papers that would revolutionize our perspective on bone and the skeleton in general.
Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells

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Neuroscience

June 30, 2020

Reliable and consistent pluripotent stem cell reporter systems for efficient purification and visualization of motor neurons are essential reagents for the study of normal motor neuron biology.
Reading frame restoration at the EYS locus, and allele-specific chromosome removal after Cas9 cleavage in human embryos

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bioRxiv

June 18, 2020

The correction of disease-causing mutations in human embryos could reduce the burden of inherited genetic disorders in the fetus and newborn.
Gon4l/Udu regulates cardiomyocyte proliferation and maintenance of ventricular chamber identity during zebrafish development

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Developmental Biology

June 15, 2020

Here we report two distinct roles of Gon4l/Udu in heart development: regulation of cell proliferation and maintenance of ventricular identity.
Stargardt Juvenile Macular Degeneration

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The New England Journal of Medicine

June 11, 2020

A 13-year-old boy was referred to the ophthalmology clinic with enlarging blind spots in the central vision in both eyes.
CD56 regulates human NK cell cytotoxicity through Pyk2

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eLife

June 8, 2020

Despite its ubiquitous expression on human NK cells the role of CD56 (NCAM) in human NK cell cytotoxic function has not been defined.
Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium

Source:

Investigative Ophthalmology & Visual Science

May 26, 2020

We tested whether sodium phenylbutyrate (4PBA) could rescue the function of mutant bestrophin 1 associated with autosomal dominant and recessive disease.
Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis

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Nature

May 15, 2020

Here we describe how selection for specific mutations that increase HSC competitive fitness, in conjunction with additional endogenous and environmental changes, drives leukaemic transformation.
Heart regeneration in mouse and human: a bioengineering perspective

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Science Direct

May 6, 2020

In this short review, we draw parallels and stress differences between heart regeneration in mice and human, from a bioengineering perspective.

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