Members

Lab Members

  • Aaron D. Viny, MD MS

    • Principal Investigator

    Dr. Viny is an assistant professor of medicine at Columbia University Vagelos College of Physician and Surgeons. He is a board-certified hematologist and medical oncologist and laboratory-based physician-scientist focusing on the study of clonal hematopoiesis, myelodysplastic syndrome, and acute myeloid leukemias. His research uses animal modeling and state-of-the-art 3-dimensional genomic techniques to uncover the genetic and epigenetic underpinnings of these diseases in order to find more precise and less toxic treatment modalities.

    Dr. Viny received his medical degree at Cleveland Clinic Lerner College of Medicine at Case Western Reserve University and completed his residency in Internal Medicine at New York-Presbyterian/Weill Cornell Medical College and fellowship in Hematology and Medical Oncology at Memorial Sloan Kettering Cancer Center.

  • Jane Jialu Xu, PhD

    • Postdoctoral Research Fellow

    Jane earned her BA in Biomedical Science at Bond University, Gold Coast, Australia. For her PhD training, she joined laboratory of Prof. Carl Walkley at St Vincent’s Institute, Melbourne, where she studied how mutation in splicing factor SRSF2 leads to myelodysplastic syndromes and chronic myelomonocytic leukemia. Jane graduated in January 2021 and then joined the Viny lab to start her postdoctoral training. Her current research projects focus on understanding how cohesin mutations alter chromatin landscape of hematopoietic cells and promote leukemogenesis. Jane is the recipient of the Walker Family Scholar fellowship. When not in the lab, she enjoys outdoors, running and cooking.

  • Yi Chen, MD PhD

    • Postdoctoral Research Fellow

    Yi Chen received his MD degree from Wenzhou Medical University, China, in 2014 and his PhD in 2022 from Karolinska Institutet, Stockholm, Sweden, in the laboratory of Dr. Felix Haglund. His graduate work applied multi-omics analyses to the pathogenesis of sarcomas (synovial sarcoma, Ewing sarcoma, chondrosarcoma, etc.) and proposed a molecular subtyping scheme and a clonal evolutionary model of synovial sarcoma. During his PhD, Yi joined Dr. Janne Lehtiö’s group at SciLifeLab, Sweden, on exchange, where he used high-resolution quantitative proteomics to identify candidates for therapy de-escalation in early HER2-positive breast cancer. Yi joined the Viny lab in 2022 to begin his postdoctoral training, with a joint appointment in the laboratory of Dr. Raul Rabadan from 2022 to 2025. His research combines existing and novel bioinformatic approaches with machine learning and AI to determine how chromatin structural changes shape normal and malignant bone marrow function, with a particular focus on cohesin-mutant myeloid neoplasms and the integration of chromatin architecture, epigenomic, and transcriptomic data to identify epigenetic biomarkers of therapeutic response in patients with MDS and AML. He also develops machine learning and deep learning methods for multi-omic data integration and clinical prediction in cancer. He is a recipient of the 2026–2027 Edward P. Evans Foundation MDS Fellowship, which supports his work building an integrative multi-omic framework for MDS and a Columbia-anchored MDS atlas linking molecular programs to clinical phenotypes. When he is not in the lab, he enjoys working out at the gym, singing, and exploring new places with his family.

  • Viviana Scoca, PhD

    • Postdoctoral Research Scientist
    • Blood Cancer United Career Development Program Fellow

    Viviana (Vivi) obtained her BS in Biological Sciences and her Master's degree in Genetics and Molecular Biology at Sapienza, University of Rome, before moving to Paris, France, to join Dr. Di Nunzio's laboratory at Institut Pasteur for her PhD studies. She applied fluorescence microscopy techniques to track HIV-1 in the host nucleus and investigate the viral interplay with nuclear factors in infected cells during early steps of replication. Guided by her interest in epigenetics, Viviana joined the lab in 2023 for her postdoctoral training, where she aims to identify gene regulation mechanisms linked to blood cell development and disease. Her research was funded by the American Italian Cancer Foundation and currently by Blood Cancer United. Her main focus is understanding cohesin and BAF complex cooperation in chromatin remodeling to uncover therapeutic vulnerabilities in myelodysplastic syndromes and acute myeloid leukemia. Beyond her research, Viviana is committed to fostering a positive academic environment and mentoring the next generation of cancer researchers.

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  • Meagan Sherlock, MS

    • Laboratory Manager

    Meagan Sherlock graduated in 2024 from the University of Connecticut, where she spent 4.5 years earning both her Bachelor’s in Biological Sciences and Master’s in Applied Genomics. Meagan started her research journey studying the effect of matrix metalloproteinase expression in cancer associated fibroblasts on the development of colorectal cancers under the direction of Dr. Charles Giardina at UConn. Most recently, she studied the effect of exercise on the reduction and regression of post-surgical inflammation and sepsis at Northwell Health’s Feinstein Institute for Medical Research. Meagan joined the lab in 2026 as a Laboratory Manager for both Dr. Aaron Viny’s lab and Dr. Lili Wang’s lab, who together seek to discover epigenetic therapeutics for AML and CLL, respectively. Beyond her research, she likes to spend her free time at the gym, crocheting, cooking, watching college sports (Go Huskies!) and is a huge animal lover. 

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  • Rong Deng, MD

    • Hematology and Oncology Fellow

    Rong earned his B.A. in Neuroscience and Behavior from Columbia University and subsequently worked in the laboratory of Dr. Jonathan Barasch, where he studied mechanisms of systemic iron regulation and developed novel therapeutics to treat iron overload disorders. He graduated with honors from the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo before returning to Columbia for internal medicine residency and hematology and medical oncology fellowship in the physician-scientist research track. He joined the Viny Lab as an inaugural Mark L. Heaney and Florence & Herbert Irving Scholar, where he pursues translational research integrating long-read sequencing, epigenomic profiling, and single-cell spatial proteomics to study treatment response and disease evolution in acute myeloid leukemia and myelodysplastic syndromes. His projects include developing rapid molecular diagnostics, identifying biomarkers of therapeutic response and resistance, and investigating how altered chromatin organization reshapes megakaryocyte development and platelet production. He is currently supported by an NIH-funded TL1 training award through the New York Consortium for Interdisciplinary Training in Kidney, Urological, and Hematological Research (NYC-KUHR). Outside the lab, Rong enjoys biking, rooting for New York sports teams, and hot pot.

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  • Amy Song, MD

    • Resident Physician

    Amy graduated from the combined seven-year medical program through The College of New Jersey and Rutgers New Jersey Medical School, during which she was inducted into the Alpha Omega Alpha and Gold Humanism Honor Societies. Starting in medical school, she investigated the clonal dynamics of the isocitrate dehydrogenase (IDH) mutation in acute myeloid leukemia. She then started internal medicine residency at Columbia University Irving Medical Center, where she studied the molecular and genetic predictors of response and resistance to IDH inhibitor therapy in patients with myeloid malignancies. She was awarded an NCI R38 CAPRI training grant and joined the Viny lab, to pursue translational and outcomes research focused on myeloid malignancies. Her current project aims to study epigenetic remodeling associated with hematologic response to IDH inhibition. In her free time, she enjoys running, exploring new cafes, and traveling.

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  • Kalliopi Chatzis, MS

    • Staff Associate

    Kalliopi earned her B.A. in Natural Science with a concentration in Cell and Molecular Biology from Fordham University and her M.S. in Biochemistry and Cell Biology from Stony Brook University. At Stony Brook, her research focused on the role of ACER2 and sphingosine-1-phosphate in breast cancer. She began her genomics career in 2021 when she joined the Integrated Genomics Operation at Memorial Sloan Kettering Cancer Center. Her four years at IGO were spent specializing in next-generation sequencing and high-throughput genomics workflows, including RNA-seq, ATAC-seq, ChIP-seq, whole-exome sequencing, and hybridization capture for MSK-IMPACT and MSK-ACCESS. During her time at MSK, Kalliopi also helped establish a new GLP-compliant laboratory wing, contributing to its early development through protocol and SOP creation, documentation systems, workflow design, and quality assurance planning. Outside of the lab, Kalliopi enjoys baking, traveling, and staying involved in her Greek community.

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  • Edna Stewart

    • PhD Candidate

    Edna is a PhD candidate in the Biomedical Engineering Department at Columbia University. She is interested in utilizing integrative omics & novel computational approaches to investigate the role of epigenetic modifications and chromatin structure in the development of hematopoietic disorders. Before graduate school, she received her B.A. in Molecular & Cell Biology at University of California, Berkeley in 2018, and worked as a Research Associate at the Chan Zuckerberg Biohub and UPSIDE Foods, a lab-grown meat startup. Edna is a T32-funded scientist. Outside the lab, she loves to run & weight-lift.

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  • Aiden Schiller

    • Research Technician

    Aiden Schiller earned his BA in Biology from Columbia University, through the dual-degree program with the Jewish Theological Seminary. During his undergraduate summers, he worked in Dr. Neil O’Brien’s lab at UCLA, studying extracellular proteins as targets for monoclonal antibody therapy. Given his interest in cancer research, Aiden joined Dr. Aaron Viny’s lab at Columbia University Irving Medical Center, where he volunteered for several years studying STAG2-knockout AML cell lines and their differential response to the FLT3 inhibitor Gilteritinib, with a focus on TGF-β mRNA upregulation. Beyond the bench, Aiden volunteers at NewYork-Presbyterian in the oncology ward and Cardiac Service Line, and in his free time enjoys playing guitar, watching movies, and weightlifting.

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  • Theo Makler, BS

    • VP&S Medical Student

    Theo earned a BS in Aeronautics and Astronautics at Stanford University, where he worked in the Bertozzi Lab with Dr. Kevin Bruemmer studying the role of protein glycosylation in neurofibromatosis type 1. Theo graduated in June 2025 and then matriculated at Columbia University Vagelos College of Physicians and Surgeons for his M.D. degree. His current work focuses on the role of Stag2 in megakaryopoiesis and its effect on megakaryocyte functionality. He is the recipient of the 2026 ASH HONORS award. In his free time, Theo enjoys flying planes, photography, watching Formula 1, and running.

  • Amanda Hill

    • VP&S Medical Student

    Amanda completed her B.S. in Biological Chemistry at the University of Chicago, where she working in the Rebay lab studying MAPK signaling in Drosophila photoreceptor differentiation. After graduation, Amanda moved to NYC to work in the Mlodzik lab at Mount Sinai. She joined the MD/PhD program at Columbia in 2025. As a rotation student in the Viny lab, she studies erythropoiesis and the cell cycle. If not looking at cells, Amanda is probably climbing, running, or backpacking.

  • Geovanna Neira

    • Administrative Assistant

    Geovanna is an administrative assistant in the Department of Medicine, Division of Hematology and Oncology. She first joined Columbia University Medical Center in 2017 as a patient service representative in the division of Hematology and Oncology. Geovanna decided to pivot her career from retail/hospitality into healthcare after her mother’s passing due to ovarian cancer. As a Washington Heights native, she is grateful to be part of an impactful medical team that serves her community. In her free time, Geovanna enjoys relaxing at the beach, trying new restaurants, and building Legos with her son.

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