Trainee Opportunities

Postdoctoral Research Fellow- Quinn Lab

The Department of Ophthalmology is seeking a full time Postdoctoral Research Fellow for a 2 year project. Our projects are aiming to use gene therapy to tackle inherited retinal disorders (IRDs). Research approaches include gene augmentation, genome editing, in vivo studies in IRD mouse models, and induced pluripotent stem cell (iPSC) retinal organoid modeling.

Job Responsibilities:

  • Conduct research experiments in accordance with laboratory and safety protocols
  • Perform assignments which are non-routine and vary in complexity with minimal direction
  • Comply data and compute results for a variety of research procedures, tests, and techniques
  • Maintain in vitro cultures
  • Mice colony maintenance and procedures with mice such as injections and surgeries
  • Experiments with animal tissues, sample collection
  • Performing characterization of retinal function and structure in rodent models (ERG,OCT fundoscopy, behavior testing), gene therapy and/or virology
  • Preparing buffers media, and running the in vitro and in vivo assays
  • Perform cell and molecular biology experiments related to DNA, RNA and protein from cell, animal or clinical specimen
  • Generation of isogenic controls from patient iPSCs using prime editing
  • Differentiations and maintenance of retinal organoids from iPSCs
  • Maintaining records of the experiment results
  • Data management, ordering supplies and updating the inventory
  • Organizing lab and regular maintenance of equipment.
  • Read scientific literature, participate in journal club, review manuscripts and present data in meetings
  • Perform manuscript writing

Minimum Qualifications:

  • Ph.D. in Biology, Neurology or related field
  • Working knowledge of laboratory equipment and research protocols
  • Ability to work with animal experiment
  • Knowledge of computer analysis techniques
  • Ability to provide routine analysis and interpretation of research data

Preferred Qualifications:

  • Background in Ophthalmic Gene Augmentation and/or iPSC derived retinal organoid modeling

Apply Here