UPDATED: Spring Stem Cells, Genome Engineering and Regenerative Medicine Lectures

October 19, 2020

Stem Cells, Genome Engineering and Regenerative Medicine Course (BMENE6510)

The lectures held Thursdays 1:00 – 3:00 PM will include general lectures on stem cell biology followed by student presentations and discussion of the primary literature. Guests not registered for the course are also welcome, please contact the course instructors for more information.

Prerequisites: (BMEN E4001) or (BMEN E4002) and Biology, Cell Biology

The themes to be presented include:

  1. Genome Engineering with CRISPR, TALEN and ZFN in stem cells
  2. Basic stem cell concepts
  3. Basic cell and molecular biological characterization of endogenous stem cell populations
  4. Concepts related to reprogramming
  5. Directed differentiation of stem cell populations
  6. The use of stem cells in disease modeling or tissue replacement/repair
  7. Stem cells in regenerative medicine

For more information, contact any of the Course Directors:

Teaching Assistant:


1/14/21 Gordana Vunjak-Novakovic, University & the Mikati Foundation Professor, Columbia U: Stem Cells in Tissue Engineering​

1/21/2021 David Schaffer, Hubbard Howe Jr. Distinguished Professor of BME, UC Berkeley: Stem cell replacement therapy

1/28/2021 Juan Carlos Izpisua Belmonte, Roger Guillemin Chair, Salk Institute for Biological Sciences: Stem-cell models of human aging and aging-associated diseases​

2/4/2021 Janet Rossant, University Professor, University of Toronto; President Emerita, International Society for Stem Cell Research (ISSCR): Stem cell development and cell differentiation in the developing embryo

2/11/2021 Ronald McKay, Founder, Lieber Institute for Brain Development, Johns Hopkins; President emeritus, ISSCR: Stem cells and the development of the nervous system

2/18/2021 Hans-Willem Snoeck, Professor of Medicine (in Microbiology & Immunology), Columbia U: Directed differentiation-Recapitulate development

2/25/2021 David R. Liu, Richard Merkin Professor; Director, Merkin Institute of Transformative Technologies; Vice Chair of faculty, Broad Institute of Harvard and MIT; Professor, Harvard University: Genome engineering: base editing and prime editing

3/4/2021 Jianlong Wang, Professor Department of Medicine and CSCI: Pluripotent and Cancer stem cells

3/11/2021 Emmanuelle Passegué, Director, Columbia Stem Cell Initiative; Alumni Professor of Genetics and Development, Columbia U: Endogenous Stem Cell Populations / HSCs / Stem Cell Aging

3/18/2021 Danwei Huangfu, Associate Professor Developmental Biology Program, Sloan Kettering Institute: Precision gene editing and large-scale CRISPR screening in hPSCs

3/25/2021 Botond Roska, Founding Director and Senior Group Leader, IOB; Professor, University of Basel, Switzerland: Visual circuits and optogenetic therapy

4/1/2021 Christian M. Metallo, Associate Professor of BME, UCSD: Stem cell metabolism

4/8/2021 Joseph Wu, Simon H. Stertzer, MD, Professor of Medicine & Radiology, Director, Stanford Cardiovascular Institute: Cardiac Stem Cells

4/15/2021 Hynek Wichterle, Jerry and Emily Spiegel Professor in the Departments of Pathology & Cell Biology and Neuroscience (in Neurology), Columbia U: Neuronal Stem Cells

4/22/2021 Pete Coffey, Professor, University College London: Neuralised human embryonic stem cells (HESCs) to repair retinal disease