Spring 2023 Stem Cells, Genome Engineering and Regenerative Medicine Course

The lectures held Thursdays 1:00 – 3:00 PM will include general lectures on stem cell biology followed by student presentations and discussion of the primary literature. Guests not registered for the course are also welcome, please contact the course instructors for more information.

The themes to be presented include:

  1. Genome Engineering with CRISPR, TALEN and ZFN in stem cells
  2. Basic stem cell concepts
  3. Basic cell and molecular biological characterization of endogenous stem cell populations
  4. Concepts related to reprogramming
  5. Directed differentiation of stem cell populations
  6. The use of stem cells in disease modeling or tissue replacement/repair
  7. Stem cells in regenerative medicine
  8. Current Therapies for Alzheimer’s disease, various Retinopathies and other diseases

For more information, contact any of the Course Directors:

Teaching Assistants:


  • First four lectures: P&S Building, 630 W. 168th Street, W. Duane Todd Amphitheater, room 16-405
  • All subsequent lectures: Edward Harkness Eye Institute, 635 W. 165 Street, 7th floor lecture hall

Extra Credit Opportunities:

  • Lunch Lecture 12pm on 2/23/2023 (pizza will be provided)
  • Lunch Lecture 12pm on 4/13/2023 (pizza will be provided)


1/19/23 Dieter Egli, Maimonides Associate Professor of Developmental Cell Biology at Columbia University: SCNT, iPSCs, & Reprogramming

1/26/23 Botond Roska, Group Leader of the Central Visual Circuits & Human Retinal Circuit Groups Institute of Molecular and Clinical Ophthalmology Basel Professor, University of Basel, Switzerland: Visual circuits and optogenetic engineering

2/2/23 Andrew Anzalone, Scientific Co-founder at Prime Medicine, Inc: Prime Editing and beyond

2/9/23 Chia-Wei Cheng, Assistant Professor of Genetics and Development at Columbia University Irving Medical Center: Stem cell metabolism I

2/16/23 Ronald McKay, Founder, Lieber Institute for Brain Development, Johns Hopkins; President emeritus, ISSCR: Stem cells and the development of the nervous system

2/23/23 Aaron Viny, Assistant Professor of Medicine at Columbia University Vagelos College of Physicians and Surgeons: Cancer stem cells

3/2/23 Hynek Wichterle, Jerry and Emily Spiegel Professor in the Departments of Pathology & Cell Biology and Neuroscience (in Neurology), Columbia University: Neuronal stem cells

3/9/23 Kapil Bharti, Senior Investigator, Ocular and Stem Cell Translational Research Section, National Eye Institute, NIH: 3D culture of Stem Cells/organoids

3/23/23 Joanna Smeeton, H.K. Corning Assistant Professor Rehabilitation and Regenerative Medicine Research (in Rehabilitation and Regenerative Medicine) (in Genetics and Development): Regenerative medicine

3/30/23 Janet Rossant, University Professor, University of Toronto & President Emerita, International Society for Stem Cell Research (ISSCR): Stem cell development and cell differentiation in the developing embryo

4/6/23 Bruce Conklin, Deputy Director, Innovative Genomics Institute, University of California: Professor of Pharmacology and Medical Genetics, University of California, San Francisco (UCSF); Senior Investigator at the Gladstone Institutes: Stem Cells and Genome Engineering

4/13/23 Hans-Willem Snoeck, Professor of Medicine (in Microbiology & Immunology), Columbia University: Human mouse chimera/organoids

4/20/23 Emmanuelle Passegué, Director, Columbia Stem Cell Initiative; Alumni Professor of Genetics and Development, Columbia University: Endogenous Stem Cell Populations / HSCs / Stem Cell Aging

4/27/23 Heather Christofk, Director, Basic and Translational Research Jonsson Comprehensive Cancer Center, UCLA: Stem cell metabolism II


Thank you to our sponsors of the course:

  • Agilent
  • biotechne
  • Synthego
  • ThermoFisher Scientific