The American Society of Hematology Honors Emmanuelle Passegué, PhD, with the 2019 William Dameshek Prize

The 2019 William Dameshek Prize was awarded to Emmanuelle Passegué, PhD, of Columbia University Irving Medical Center in New York City during the Annual Meeting of the American Society of Hematology (ASH) held December 2019 in Orlando, FL. Dr. Passegué has made seminal contributions to the understanding of the biology of blood-forming stem cells. Her work focuses on changes that happen to stem cells in the contexts of myeloid malignancies and physiological aging. Notably, she discovered a potential strategy for correcting impaired blood production in the elderly by identifying specific biological mechanisms that are altered when stem cells age and become dysfunctional. Her other discoveries have implications for blood cancers and bone marrow failure syndromes. She defined the unique susceptibility of stem cells to certain types of DNA damage, from such sources as ultra-violet rays and x-ray machines and described how these cells’ specific repair mechanisms can render them vulnerable to disease-causing mutations. Dr. Passegué’s scientific contributions have been previously recognized with an ASH Scholar Award and an NHLBI Outstanding Investigator R35 grant. She has served as vice-chair and chair of the ASH Scientific Committee on Myeloid Biology and as an abstract and award study section reviewer.

“I am delighted to be recognized for such a prestigious award as the William Dameshek Prize and humbled by its significance and broad renown,” said Dr. Passegue. “This is a rewarding recognition of my work from my peers.”

The William Dameshek Prize is awarded to an early- or mid-career hematologist who has made a recent outstanding contribution to the field of hematology. This prize is named after the late William Dameshek, MD, a past president of ASH and the original editor of the Society’s flagship journal, Blood. 

“Dr. Passegué is an impressive investigator who has clearly accomplished so much, all within 10 years of starting her own laboratory,” said ASH President Dr. Roy Silverstein. “Her discoveries have illuminated this field of hematology research, and I am honored to present Dr. Passegué with the William Dameshek Prize.”

The American Society of Hematology (ASH) ( is the world’s largest professional society of hematologists dedicated to furthering the understanding, diagnosis, treatment, and prevention of disorders affecting the blood. For 60 years, the Society has led the development of hematology as a discipline by promoting research, patient care, education, training, and advocacy in hematology. ASH publishes Blood (, the most cited peer-reviewed publication in the field, which is available weekly in print and online, as well as the newly launched, online, peer-reviewed open-access journal, Blood Advances (